Progress in image-guided radiotherapy for the treatment of nonsmall cell lung cancer

• 作者: Jing Li Qiang Lin Xiao-Cang Ren Yue-E Liu
• 来源期刊: 世界放射学杂志:英文版(电子版)
• 学科: 医学
• 关键词: NON-SMALL cell LUNG cancer RADIOTHERAPY IMAGE-GUIDED RADIOTHERAPY INTENSITY-MODULATED POSITIONING error
• 年，卷（期）: 2019,（3）
• 页码范围: 46-54
• 页数: 9页
• 分类号: R

摘要

Lung cancer is one of the most common malignant tumors. It has the highest incidence and mortality rate of all cancers worldwide. Late diagnosis of nonsmall cell lung cancer (NSCLC) is very common in clinical practice, and most patients miss the chance for radical surgery. Thus, radiotherapy plays an indispensable role in the treatment of NSCLC. Radiotherapy technology has evolved from the classic two-dimensional approach to three-dimensional conformal and intensity-modulated radiotherapy. However, how to ensure delivery of an accurate dose to the tumor while minimizing the irradiation of normal tissues remains a huge challenge for radiation oncologists, especially due to the positioning error between fractions and the autonomous movement of organs. In recent years, image-guided radiotherapy (IGRT) has greatly increased the accuracy of tumor irradiation while reducing the irradiation dose delivered to healthy tissues and organs. This paper presents a brief review of the definition of IGRT and the various technologies and applications of IGRT. IGRT can help ensure accurate dosing of the target area and reduce radiation damage to the surrounding normal tissue. IGRT may increase the local control rate of tumors and reduce the incidence of radio-therapeutic complications.