Therapeutic effect of Liyan Baidu decoction combined with oxygen spray on radioactive stomatitis in patients with nasopharyngeal carcinoma

• 作者: Guang-Ying Hou Jian-Wei Hu Jun-Jun Miao Lei Gao Mang-Mang Cui Xiang-Kun Yuan Yong-Xia Zhang Zi-Wei Qi
• 来源期刊: TMR肿瘤
• 学科: 医学
• 关键词: RADIOACTIVE mouth PHARYNGITIS OXYGEN SPRAY New rehabilitation Clinical observation
• 年，卷（期）: 2019,（2）
• 页码范围: 162-169
• 页数: 8页
• 分类号: R

摘要

Objective: To observe the efficacy of Liyan Baidu Decoction combined with Oxygen Spray in the treatment of radiation oropharyngeal cancer in patients with nasopharyngeal carcinoma. Methods: Forty patients with radionomephicitis of nasopharyngeal carcinoma from 2015.03-2017.05 were randomly divided into treatment group (27 cases) and control group (23 cases). The treatment group was treated with Liyan Baidu Decoction combined with oxygen spray;the control group was treated with rehabilitation fluid. Results: Compared with the control group, the time of oral mucosal reaction was delayed (P < 0.05), the cumulative radiation of oral mucosal reaction increased (P < 0.05), and the oral mucosal reaction index decreased (P < 0.05). The degree of salivary gland damage was decreased (P < 0.05), and most of the KPS scores were improved compared with before treatment. However, the quality of life of Liyan Baidu Decoction group was higher than that of the control group (P < 0.05). Conclusion: Liyan Baidu decoction combined with oxygen spray may effectively delay the time of acute radioactive oral mucosal reaction in patients with nasopharyngeal carcinoma, and effectively reduce the radiation oral mucosal damage and salivary gland damage in patients with nasopharyngeal carcinoma. This study provides a clinical basis for the application of Liyan Baidu Decoction.