New Insights into the Discovery of Novel Drugs to Treat Human Pulmonary Adenocarcinoma

• 作者: Haishan Zhang Lining Wang Yingxin Chen Yu Wang
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: CISPLATIN DOCETAXEL PEMETREXED ADENOCARCINOMA In VITRO In Vivo Clinical Trial
• 年，卷（期）: 2019,（2）
• 页码范围: 178-187
• 页数: 10页
• 分类号: R73

摘要

Lung cancer is one of the most prevalent cancers in the world. A cisplatin-based chemotherapy regimen is commonly used to major patients who have adenocarcinoma. Because of the limited remission rate, many patients need receive second-line treatment after receiving first-line chemotherapy. Drug screenings carried out currently are mainly from single phase. In consideration of systemic treatment, evaluation of a novel drug candidate from the point of view of first-line and second-line treatment is supposed to be important in the process of drug screening. In this review, we propose a flow of searching for new drugs, which is tailored to accommodate to first-line and second-line treatment in clinic.