In clinic, most patients with middle-late cancer suffer from cancer pain, which seriously affects the confidence and compliance of treatment. However, the side effects of the three-step analgesic therapy, which is widely used at present, are gradually manifested, aggravating patients' resistance to treatment. The role of Moxibustion in relieving pain has been gradually recognized and used in various professional fields. Because of its advantages of non-toxic side effects, simple operation, economic benefits, pain relief and immunity enhancement, moxibustion has been paid more and more attention.