Research progress of epigenetic modification in autophagy regulation

• 作者: Hong-Wu Wang Huan-Tian Cui Wan-Tao Xiong Wei-Bo Wen Yu-Ting Li Zhai-Yi Zhang
• 来源期刊: 精准医学研究
• 学科: 医学
• 关键词: AUTOPHAGY SIGNALING PATHWAY EPIGENETICS
• 年，卷（期）: 2019,（4）
• 页码范围: 96-102
• 页数: 7页
• 分类号: R73

摘要

Autophagy can maintain the homeostasis of cells by removing the accumulated proteins,damaged organelles and pathogens.Studies have shown that autophagy is closely related to a variety of life activities,and its dysfunction often leads to tumor,degenerative diseases and other diseases.Epigenetic modification is widely involved in autophagy and plays an important role in the occurrence and development of many diseases.In order to further understand the mechanism of autophagy,we review the related signaling pathways and epigenetic modifications of autophagy.