The mechanism and traditional Chinese medicine research of bone destruction and hypercalcemia in multiple myeloma

• 作者: Xue Wang
• 来源期刊: TMR理论与假说
• 学科: 医学
• 关键词: Multiple MYELOMA BONE DESTRUCTION HYPERCALCEMIA Traditional Chinese MEDICINE research
• 年，卷（期）: 2019,（3）
• 页码范围: 225-228
• 页数: 4页
• 分类号: R

摘要

Multiple myeloma is a malignant proliferative disease of plasma cells. Its main feature is the malignant proliferation of monoclonal plasma cells and the secretion of a large number of monoclonal immunoglobulins. Because of the uncontrolled proliferation, extensive infiltration of malignant plasma cells, and the appearance and deposition of a large number of monoclonal immunoglobulins, normal polyclonal plasma cell proliferation and polyclonal immunoglobulin secretion are inhibited. It can cause extensive bone destruction, hypercalcemia, repeated infection, renal insufficiency, high viscosity syndrome and other clinical manifestations, which can alsolead to adverse consequences.In view of these unique clinical manifestations and pathological features of multiple myeloma, we systematically expounded the pathological characteristics of multiple myeloma and the treatment of traditional Chinese medicine from extensive bone destruction and hypercalcemia on the basis of Chinese and Western medicine. In order to provide theoretical support and clinical guidance for the treatment of multiple bone marrow tumors with bone destruction and hypercalcemia.