The clinical efficacy analysis of radiofrequency ablation combined with chemotherapy in treating late non-small cell lung cancer

• 作者: Feng Xu Ying-Ying Liu
• 来源期刊: TMR肿瘤
• 学科: 医学
• 关键词: CT GUIDED RADIOFREQUENCY ablation NON-SMALL cell lung cancer QLQ-C30
• 年，卷（期）: 2019,（3）
• 页码范围: 216-221
• 页数: 6页
• 分类号: R73

摘要

Objective:To study the short-term efficacy and improvement effect on the quality of life of CT guided radiofrequency ablation(RFA)in treating late non-small cell lung cancer.Methods:317 patients with non-small cell lung cancer(87 cases in the observation group and 230 cases in the control group)were selected for propensity score matching,with a matching tolerance of 0.05,and 42 pairs were successfully paired.The changes in chest enhanced CT before and 3 months after treatment and the quality of life measurement scale EORTC QLQ-C30 in Chinese version were evaluated.Results:The disease control rate of the observation group was 88.09%,which was significantly higher than that of the control group(61.91%).The functional and symptom scores of the two groups after treatment were significantly better than those before treatment,and the indicators of the observation group after treatment were better than those of the control group(P<0.05).Conclusion:CT-guided radiofrequency ablation combined with chemotherapy is safe and effective in the treatment of NSCLC,which can control local tumor progression,reduce tumor burden,and improve the quality of life of patients with advanced NSCLC.