Percutaneous microwave ablation combined with simultaneous transarterial chemoembolization for hepatocellular carcinoma with macrovascular invasion or extrahepatic metastases

• 作者: Huadan Song Jianhua Wang Lingxiao Liu Mengfei Wu Shanshan Gao Xiaolin Wang Zhiping Yan Zhiyuan Zheng Zihan Zhang
• 来源期刊: 介入医学杂志
• 学科: 医学
• 关键词: HEPATOCELLULAR carcinoma Combination therapy Microwave ablation SURVIVAL
• 年，卷（期）: jryxzz,（2）
• 页码范围: 55-59
• 页数: 5页
• 分类号: R735.7

摘要

Objective:To evaluate the safety and efficacy of percutaneous microwave ablation(MWA)combined with simultaneous transarterial chemoembolization(TACE)in patients with hepatocellular carcinoma(HCC)patients with microvascular invasion(MVI)or extrahepatic metastases(EHM).Methods:Between August 2012 and April 2017,101 patients with MVI/EHM of HCC underwent percutaneous MWA combined with simultaneous TACE at our center.The clinical data were collected and analyzed for survival and prognostic factors.Results:The mean follow-up time was 23.6±14.7 months.One patient had grade 3 complications,and the median overall survival was 12.0 months(95%confidence interval 9.7-14.3).Multivariate analysis showed that ChildPugh class,serum alpha-fetoprotein level,and Eastern Cooperative Oncology Group performance status were independent factors of survival.Conclusion:Our results suggest that percutaneous MWA combined with simultaneous TACE is a safe and effective treatment for HCC with MVI/EHM.