Frequency of Monthly Ejaculation at Sexual Intercourse, DNA Fragmentation Index and Fertilization Rate among Sperm Donors and Fertility-Challenged Men in Sub-Saharan Africa: Paper 1

• 作者: Abayomi B. Ajayi Adedamilola Atiba Ayodeji T. Adeoye Bamgboye M. Afolabi Ibukun I. Ayelehin Ifeoluwa O. Oyetunji Joy Ehichioya Seun Saanu Victor D. Ajayi
• 来源期刊: 泌尿学期刊(英文)
• 学科: 医学
• 关键词: MONTHLY Sexual EJACULATION Rate DNA Fragmentation INDEX Male INFERTILITY Age Group Body Mass INDEX Social HABITS Black AFRICANS
• 年，卷（期）: 2019,（11）
• 页码范围: 181-194
• 页数: 14页
• 分类号: R69

摘要

Introduction: In humans, the ideal ejaculation frequency depends on age, exercise and sexual potential. Natural ejaculation frequency balances the testosterone levels in the body. Materials and Methods: Semi-structured questionnaire was used to collect information from subjects. Semen samples were collected from sperm donors and sub-fertile men who presented for infertility challenges. Processing and analysis of semen samples were done according to World Health Organization guidelines. Sperm DNA fragmentation was evaluated using the Halosperm&#174;?kit. Results: A total of 114 subjects, including 19 sperm donors and 95 sub-fertile males were studied. There was a significant difference (t =?&#8722;5.96, P-value = 0.00001) in the mean [±sd] age of sperm donors (30.8 [8.1]) and that of sub-fertile men (42.3 [76]). There was a significant difference (t=?&#8722;4.10, P-value = 0.0005) in the mean monthly ejaculation during sexual intercourse (MESI) among sperm donors with DNA fragmentation index &#8722;2.20, P-value = 0.02) in MESI among sub-fertile men aged ≥40 years (8.9 [4.6]) than among those aged &#8722;0.67, SE = 0.28, t = &#8722;2.40, P-value = 0.02, 95% CI: &#8722;1.24,?&#8722;0.10). Conclusion: In men < 40 years, fewer MESI did not worsen the DFI. A higher number of professionals such as doctors, lawyers and engineers, reported lower monthly frequency of sexual ejaculations compared to entrepreneurs. Entrepreneurs and non-smokers had the highest frequencies of MESI.