Preliminary study on Anti-inflammatory and Anti-tumor Effects of Gelatin-based on pH-responsive Drugloaded Nanoparticles

• 作者: Fen Lin
• 来源期刊: 抗癌研究
• 学科: 医学
• 关键词: DRUGS RELEASING loaded
• 年，卷（期）: kayj,（2）
• 页码范围: 18-20
• 页数: 3页
• 分类号: R73

摘要

Gelatin as one kind of nano-drug carrier is a polysaccharide which can be absorbed after releasing all nano-drugs.Poly(ethylene glycol)as a polymer material that can modify nano-drugs is able to extend circulatory time of doxorubicin and aspirin,enhance stability and reduce toxicity.At precancerous,aspirin will be released slowly to resist inflammation.When tumor cell appears at a more advance stage,doxorubicin release from Gel to achieve anti-tumor effect.After all those steps,poly(ethylene glycol)could be expelled from body.In brief,the nano-drug that has doxorubicin and aspirin is able to prevent the growth of tumor cells and kill them when they appear more precisely.