p38α MAP kinase promotes asthmatic inflammation through modulation of alternatively activated macrophages

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2019,（12）
• 页码范围: 1095-1097
• 页数: 3页
• 语种: 英文
• DOI: 10.1093/jmcb/mjz054

摘要

Dear Editor, Asthma is characterized by reversible airflow obstruction,bronchial hyperreactivity,and chronic airway remodeling (Al-Muhsen et al.,2011).Pulmonary macrophages have been implicated in asthmatic inflammation (Lee et al.,2015;Qian et al.,2015).The p38 mitogenactivated protein kinase (MAPK) plays an essential role in inflammation,but its role in asthma has not been determined (Kim et al.,2008).