Correlates of Hepatitis B Virus Infection among Antenatal Clinic Attendees of Volta Regional Hospital, Ho, Volta Region, Ghana

• 作者: Daniel A. Abaye Ernest Yeboah Boateng Joseph Otoo Paschal Kofi Dah
• 来源期刊: 应用科学(英文)
• 学科: 医学
• 关键词: BINOMIAL Logistic Regression HEPATITIS B Virus Infection ANTENATAL CLINIC Attendees
• 年，卷（期）: 2019,（7）
• 页码范围: 573-586
• 页数: 14页
• 分类号: R73

摘要

Hepatitis B virus (HBV) infection remains a global health problem. With about 380 million chronic carriers of the HBV virus, there are over two million global deaths annually. Ghana is among the high endemic countries in Africa, with HBV prevalence ranging from 4.8% to 12.3% in the general population, 10.8% to 12.7% in blood donors and about 10.6% in antenatal clinic (ANC) attendees. The main objectives of this study were to test how socioeconomic factors, risky behaviors, knowledge and awareness of HBV infection correlate with actual HBV status among antenatal clinic attendees and to determine the predictors of HBV testing among ANC attendees. The study employed random sampling technique to sample 500 pregnant women, at mothers’ clinic of Volta Regional Hospital, Ho, Ghana. A structured questionnaire was used to collect information on socio-demographic characteristics, Hepatitis B status, possible risk factors, awareness and knowledge levels of HBV infection. Cross tabulation and the chi-square (χ2) statistic were used to determine statistical independence or association of study variables. Kruskal-Wallis test was applied to test for the differences in HBV knowledge scores across HBV status and levels of HBV awareness;and the binomial regression model was used to determine the predictors of HBV testing among ANC attendees. It is evident that age, religion, ethnicity, educational level, blood transfusion, number of blood transfusions, gravidity, parity, awareness of HBV and monthly income were associated with HBV status. Results of the Binomial Logistic Regression model indicate that Age (p = 0.03), Education level (p = 0.04), Religion (p = 0.04), Ethnicity (p = 0.00) and Blood transfusion (p = 0.04) were significant (p 0.05) predictors of HBV testing. Knowledge of HBV status enables patients to seek early treatment, facilitates referral for social support and counseling. We recommend that the Ministry of Health should carry effective education on HBV and its prevention for women of child-bearing age.