Okra(Abelmoschus esculentus L.Moench)as Anti-cholesterol,Anti-diabetic and Anti-obesity in White Male Rats

• 作者: Maritsa Nurfatwa Nur Rahayuningsih Rizka Pratama Yedy Purwandi Sukmawan
• 来源期刊: 药剂与药理学:英文版
• 学科: 医学
• 关键词: Anti-cholesterol DIABETIC obesity OKRA
• 年，卷（期）: 2019,（7）
• 页码范围: 429-433
• 页数: 5页
• 分类号: R

摘要

Hypercholesterolemia is cholesterol elevation condition in blood serum.Type 2 Diabetes Mellitus is a metabolic disorder increasing significantly around the world,associated with obesity and lipid accumulation in the body.Okra(Abelmoschus esculentus L.Moench)is used as anti-obesity and anti-cholesterol empirically.The objective of the study was to determine the anti-obesity,anti-diabetic and anti-cholesterol activity of okra ethanolic extract in animal high-fat diet model.We conduct short-and long-term anti-obesity,anti-diabetic and anti-cholesterol test.The blood sample was collected from all rats after 8 hours fasting previously.Short-(p=0.000)and long-term test(p=0.005)showed significantly different parameter between the negative and positive group.Dose III showed no significant differences compared to positive group(p>0.05)in the short-term test while,Dose I,II and III showed no significant differences compared to positive group in decreasing cholesterol level in the long-term test,Dose III showed the best activity in decreasing cholesterol level in blood serum and was equivalent with the positive group.