The Nutrition Science on Basis of Algae in the Patronage of Neoplastic Processes

• 作者: Aiman Kaldybayeva Ainur Amanzholkyzy Azhar Zheksenova Emil Muhamedzhanov Farida Balmaganbetova Gulaim Taskozhina Gulbanu Mukyshova Roza Nurgaliyeva
• 来源期刊: 药剂与药理学:英文版
• 学科: 医学
• 关键词: Cancer FUCOIDAN PATHOGENESIS prevention
• 年，卷（期）: 2019,（10）
• 页码范围: 521-526
• 页数: 6页
• 分类号: R

摘要

In the mechanism of development of the tumor process, a large role is given to the impact on the body of factors causing cell death (apoptosis). Therefore, all technologies aimed at reducing the negative impact are methods of preventing the development of the tumor process. Of great interest in this regard are food compounds with high bioactivity, in particular sulfated polysaccharide brown algae fucoidan. Fucoidan prevents cell death due to antioxidant activity, anti-toxic effects, antibacterial or immunomodulatory effects, normalization of metabolic processes and neuro-endocrine status. In addition, fucoidan has a direct impact on the cancer cell: reduces its survival, improves differentiation and inhibits proliferation, suppresses migration and invasion, or blocks metastasis. This indicates that fucoidan can be used as a functional food product to prevent and treat cancer.