The occurrence of maize diseases was systematically studied at different growth stages of maize in different areas of Anhui Province. It was found that maize has a long optimal growth period in Anhui Province, and the maize planting structure is complex. The northern region is mainly planted with summer maize in large scale, while the southern region is mainly planted with spring maize in scattered pattern. In terms of diseases, the south spring maize suffered from more diverse diseases than the north summer maize. The main maize disease in Suzhou, Bozhou, Fuyang and Bengbu areas was southern rust, which was common with the highest diseased plant rate of 76%. The main maize diseases in Lu an, Anqing, Chizhou, Tongling and Xuancheng were rust, maize rough dwarf virus (MRDV), southern leaf blight and sheath blight. Other diseases such as northern leaf blight, stalk rot and maize smut occurred commonly. The diseased plant rate of maize rust was in the range of 25%-47%.