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摘要:
Keratoconus and iatrogenic keratectasia are the corneal ectatic disorders occurring due to biomechanical weakening of the cornea resulting in distorted images,myopia, and irregular astigmatism. Corneal collagen cross-linking(CXL) is performed to arrest keratoconus successfully. The main aim of this review is to discuss the safety and efficacy of the adjuvant therapies, such as the combination of CXL and photorefractive keratectomy(PRK) for the treatment of corneal ectatic disorders. A comprehensive literature search was performed using PubM ed, MEDLINE, and Scopus using keywords ‘collagen’‘keratoconus’,‘keratectasia’,‘collagen cross-linking’,and ‘photorefractive keratectomy’. Search results were restricted to clinical studies published in English. Corneal CXL effectively arrests the progression of keratoconus by enhancing corneal rigidity. However, functional vision is not improved by cross-linking. Combining CXL to refractive surgeries such as topography-guided PRK or transepithelial PRK is found to be a safe and effective method in providing corneal stability as well as significantly improving functional visual acuity with few minor complications. This combined technique also prevents regression of keratoconus and reduce the risk of keratectasia. CXL combined with PRK is a promising therapeutic approach in ophthalmology that can be successfully used to treat progressive keratoconus and other corneal ectatic disorders and to enhance visual acuity.
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篇名 Combined corneal CXL and photorefractive keratectomy for treatment of keratoconus: a review
来源期刊 国际眼科杂志:英文版 学科 工学
关键词 CORNEAL COLLAGEN cross-linking PHOTOREFRACTIVE KERATECTOMY KERATOCONUS
年,卷(期) 2019,(12) 所属期刊栏目
研究方向 页码范围 1929-1938
页数 10页 分类号 TP3
字数 语种
DOI
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研究主题发展历程
节点文献
CORNEAL
COLLAGEN
cross-linking
PHOTOREFRACTIVE
KERATECTOMY
KERATOCONUS
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
国际眼科杂志:英文版
月刊
2222-3959
西安市友谊东路269号
出版文献量(篇)
2720
总下载数(次)
2
总被引数(次)
0
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