Synthesis of anti-vicinal diboronates from diarylethynes and B2pin2

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2019,（22）
• 页码范围: 1685-1690
• 页数: 6页
• 语种: 英文

摘要

Anti-vicinal diboronates were fabricated from easily available diarylethynes and B2pin2 via a basecatalyzed domino-borylation-protodeboronation (DBP) strategy under transition-metal-free conditions.Under the standard conditions,reactants with a range of different classes of functional groups on the rings,such as MeO,MeS,CF3O,Me2N,TMS,I,Br,Cl,F,and the thiophene ring,were tolerated.Downstream transformation of the vicinal diboronates provided a facile pathway for obtaining vicinal diols by mild oxidation with NaBO3,and a new deuteriation technique was developed in order to acquire 1,2-diarylethanes-1,2-d2 and 1,2-diarylethanes-1,1,2,2-d4.The new deuteriation strategy developed in this study may provide a new research direction for deuteriation chemistry.