Effect of Non-Surgical Periodontal Therapy on the Severity of Rheumatoid Arthritis—A Clinical and Hematological Study

• 作者: Monali Amit Shah Rujuta Krishnakant Pandya Yesha Hareshkumar Raval
• 来源期刊: 口腔学期刊(英文)
• 学科: 医学
• 关键词: Chronic PERIODONTITIS RHEUMATOID ARTHRITIS DAS28
• 年，卷（期）: 2020,（1）
• 页码范围: 1-9
• 页数: 9页
• 分类号: R59

摘要

Background: The epidemiological and pathological relations between Periodontitis and Rheumatoid arthritis (RA) have been stated. The citrullination and attendant autoantibody responses are defining features of RA. It has been recognized that the oral bacteria, inflammation and its mediators might play an important role in RA activity. Hence this study aimed to evaluate the effect of Non-surgical Periodontal Therapy in reducing the severity of Rheumatoid arthritis. Materials and Method: Totally 25 participants diagnosed with RA and Periodontitis were included in the study. Clinical parameters such as CPSS index, BOP% and CAL, estimation of ESR and calculation of DAS28 done at baseline, after Pre-NSPT and after next Post-NSPT were recorded. Results: Statistically significant improvement was noted for CPSS (p < 0.001), BOP% (p < 0.001) and CAL (p < 0.001) after NSPT. The ESR values also showed significant reductions (p < 0.001) and the DAS28 scores also showed statistically significant improvements (p Conclusion: Reduction in the periodontal inflammation positively affects the rheumatoid arthritis activity, hence improving the patient’s health.