Fecal microbiota transplant for more than Clostridioides difficile: Dermatology a new frontier

• 作者: Aaron M Secrest Ashley M Snyder James Abbott M Kyle Jensen
• 来源期刊: 世界皮肤病学杂志
• 学科: 医学
• 关键词: Fecal microbiota transplantation Skin diseases DERMATOLOGY RETROSPECTIVE Clostridium difficile Inflammation
• 年，卷（期）: 2020,（2）
• 页码范围: 10-12
• 页数: 3页
• 分类号: R57

摘要

Fecal microbiota transplant(FMT)has quickly become popular in research not only for recurrent Clostridioides difficile infections but for other chronic conditions as well.Recent,small dermatologic studies have reported improvements in inflammatory skin conditions in individuals treated with FMT,but larger studies are needed to clarify this possible relationship between the skin and the gut microbiome.We conducted a single-center,retrospective chart review to assess changes in acne,dermatitis herpetiformis and/or celiac disease,eczema,and psoriasis.Due to the retrospective nature of this study and the limitations of the current electronic medical record,we were unable to adequately assess cases of these diseases in relation to FMT.However,this study informs us that improvements in retrospective data are needed to formally evaluate this possible association.The better,but more cumbersome,study design would be a prospective,observational study.We encourage others to pursue further interdepartmental research on the influence of the gut microbiome on inflammatory skin diseases.