To systematically evaluate the clinical efficacy and safety of acupuncture in treating cancer-related insomnia.Methods:Randomized controlled trials(RCTs)and quasi-randomized controlled trials of acupuncture in the treatment of cancer-related insomnia were searched by computer in a Pubmed database,and the retrieved literature was screened according to inclusion and exclusion criteria.After the literature screening was completed,two reviewers read the literature titles independently and extracted effective information.The migration risk assessment was performed by Cochrane.All statistical calculation requirements for this study were fully completed by RevMan5.3 software.Results:Among the 68 selected works of literature,3 RCTs were finally included,with a total of 133 patients.The risk of research bias is generally very low.In 3 RCTs,the sleep score of the experimental group was decreased by 0.48 more than that of the control group in 3 RCTs,with a 95%confidence interval of-0.82 and-0.13,and the degree of decrease was statistically significant(Z=2.70,P<0.05).Conclusion:Higher levels may indicate that acupuncture-related therapies are more effective in improving cancer-related insomnia.Although the included literatures feature low bias and no heterogeneity,the number may have reduced its clinical significance.Therefore,more studies on high-quality randomized controlled trials should be conducted in the future to better clarify the therapeutic effect of acupuncture and moxibustion on cancer-related insomnia.