Hypothesis of design of biological cell robot as human immunodeficiency virus vaccine

• 作者: Fan Yang Xiao-Yu Liao Yao-Ying Xie
• 来源期刊: 世界病毒学杂志
• 学科: 工学
• 关键词: Human immunodeficiency virus New vaccine Biologically inspired microrobots Human immunodeficiency virus target cell surrogate CD4
• 年，卷（期）: 2020,（3）
• 页码范围: 19-26
• 页数: 8页
• 分类号: TP2

摘要

High genetic variability of human immunodeficiency virus(HIV)has been a major intractable challenge to the practical design of vaccines.But a recent pioneer study published in PNAS Xenobots,is likely to revolutionize HIV prevention as it presented the world's first living robot made of cells.In the advent of this discovery,we herein discuss the possibility of using living biological cell robots to target HIV-infected T lymphocytes,and the prospects of this approach being a new HIV vaccine.We capture the current research status and trend of advances in biological cell robots'design as a new HIV vaccine.The key differences between this novel vaccine and other HIV vaccines are highlighted.