The law of the prescription for non-alcoholic steatohepatitis: a data mining analysis

• 作者: Bin Hao Feng-Yuan Zhang Teng-Fei Bai Xiao-Ting Ma
• 来源期刊: TMR医学数据挖掘
• 学科: 医学
• 关键词: TRADITIONAL Chinese MEDICINE Non-alcoholic STEATOHEPATITIS Data mining PRESCRIPTION
• 年，卷（期）: tmrxysjwj_2020,（1）
• 页码范围: 28-36
• 页数: 9页
• 分类号: R73

摘要

Objective:This study aimed to explore the law of the prescription for non-alcoholic steatohepatitis and provide ideas for the clinical application.Methods:This study searched CNKI,Wanfang,CBM,VIP,Web Of Science,PubMed,Elsevier to identify the studies published in nearly three years.The Chinese Medicine Heritage Supporting Platform(V2.5)was used to analyze traditional Chinese medicines used in the treatment of nonalcoholic steatohepatitis prescriptions and their combination rules,extract core combinations to form a new formula.Results:A total of 58 commonly used prescriptions for the treatment of non-alcoholic steatohepatitis were retrieved,including 96 flavors of traditional Chinese medicine.Data mining showed that Chinese medicine with frequency≥6 had a total of 21 flavors,and common pairs of drugs and 26 pairs were used to treat nonalcoholic steatohepatitis.The core drug combination was 6 pairs and evolved into a new party with 3 pairs.Conclusion:The traditional Chinese medicine inheritance platform system has important value for the clinical trial of traditional Chinese medicine for the treatment of nonalcoholic steatohepatitis.The new evolution of the Chinese medicine provides a new idea for the clinical treatment of non-alcoholic steatohepatitis.