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摘要:
The goals of asthma management are to prevent or minimize symptoms, avert or reduce risk of asthma attacks and to ensure that asthma does not limit the patient’s activities since it is not curable. Thus in this study, the degrees of success following treatments given to patients over time were assessed based on the patient’s length of stay on admission and factors responsible for patients’ response to treatment were equally examined using survival analysis models of parametric and semi-parametric distributions. The study was conducted on 464 asthmatic patients from four different hospitals in Ogun State. The data were extracted from patients’ records and prognostic factors such as age, sex, smoking, hereditary, obesity, respiratory illness and environmental pollution were considered for survival analysis. It was observed that there was drastic reduction in survival rate from 7 days upward at a cut-off probability value of 0.485, based on Kaplan-Meier (KM) results. Log-normal regression model, a parametric model with the least AIC value (2969.74) and least negative Log likelihood value (1475.87) shows best performance in handling asthma data with prognostic factors of Smoking (HR = 1.32, 95% CI: 0.93 - 1.88), Obesity (HR = 1.25, 95% CI: 0.80 - 1.93), Environmental pollution (HR = 0.79, 95% CI: 0.52 - 1.18) and Respiratory illness (HR = 1.93, 95% CI: 1.33 - 2.79) were found to have significantly affected the length of stay of asthmatic patients in hospital.
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篇名 On the Survival Assessment of Asthmatic Patients Using Parametric and Semi-Parametric Survival Models
来源期刊 职业病与环境医学(英文) 学科 医学
关键词 Asthma Disease Cox Regression Model Hazard Rates PARAMETRIC Regression MODELS PROGNOSTIC Factors
年,卷(期) 2020,(2) 所属期刊栏目
研究方向 页码范围 50-63
页数 14页 分类号 R56
字数 语种
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Asthma
Disease
Cox
Regression
Model
Hazard
Rates
PARAMETRIC
Regression
MODELS
PROGNOSTIC
Factors
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
职业病与环境医学(英文)
季刊
2333-3561
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
61
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0
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0
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