A review on the Pharmacology and Adverse Drug Reaction of Chaihu Herbal Injection

• 作者: Cui-Hong Zhu Dan Chen Jia-Wen Zhao Xiao-Yan Wang Xue Yang
• 来源期刊: 亚洲毒理学研究
• 学科: 医学
• 关键词: Chaihu HERBAL INJECTION RADIX Bupleuri Chaihu TOXICOLOGY ADVERSE drug reaction PHARMACOLOGY
• 年，卷（期）: 2020,（1）
• 页码范围: 42-47
• 页数: 6页
• 分类号: R28

摘要

The Chaihu herbal injection was the first herbal injection to be developed and used in China,which has been used in clinic for more than 70 years.This injection is widely used to treat fever caused by influenza or common cold and malaria.However,there is an ongoing debate about the safety of the clinical use of Chaihu herbal injection in view of the large number of adverse drug reaction reports and literature in China.On May 29,2018,the China Food and Drug Administration issued a notice requiring to revise the instruction manual of Chaihu herbal injection,list"prohibit for children"under the taboo item,and add the warning"adverse reactions of this product include anaphylactic shock".The purpose of this review is to provide updated,comprehensive information on the pharmacology and adverse drug reaction of Chaihu herbal injection based on scientific literatures in the past few decades.