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摘要:
Background:Gongxuening capsule is a Chinese patent medicine for treating the dysfunctional uterine bleeding.We report a meta-analysis of the combination efficacy between conventional medicines with Chinese patent drug Gongxuening in the treatment of dysfunctional uterine bleeding.Materials and methods:Seven databases were used to retrieve the relevant research of Chinese patent drug Gongxuening treatment for dysfunctional uterine bleeding from the databases establishment to 2020.The data were extracted independently by 2 researchers according to the described selection research.The meta-analysis was performed using RevMan5.3 software.Results:This study included 23 randomized trials,with a total of 1,836 dysfunctional uterine bleeding patients.Chinese patent drug Gongxuening could significantly improve the effective rate,and reduce endometrial thickness,control bleeding time,complete hemostasis time and sex hormone level,and no serious adverse events.Based on sensitivity analysis and subgroup analysis,the heterogeneity sources of endometrial thickness,complete hemostasis time and sex hormone level were found.In follicle stimulating hormone and luteinizing hormone,there was no significant difference between the two groups when Chinese patent drug Gongxuening combined with desogestrel ethinylestradiol.Conclusion:Conventional medicines combined with Chinese patent drug Gongxuening can make patients with dysfunctional uterine bleeding achieve better effective rate,and no serious adverse events occurred.
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篇名 The therapeutic efficacy and safety of Gongxuening capsule in dysfunctional uterine bleeding:a systematic review and meta-analysis
来源期刊 TMR医学数据挖掘 学科 医学
关键词 Gongxuening capsule Conventional medicines Dysfunctional uterine bleeding META-ANALYSIS Systematic review
年,卷(期) 2020,(4) 所属期刊栏目
研究方向 页码范围 152-165
页数 14页 分类号 R57
字数 语种
DOI
五维指标
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研究主题发展历程
节点文献
Gongxuening
capsule
Conventional
medicines
Dysfunctional
uterine
bleeding
META-ANALYSIS
Systematic
review
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
TMR医学数据挖掘
季刊
2624-1587
天津市河东区大直沽中路伯苓大厦B座906
出版文献量(篇)
40
总下载数(次)
2
总被引数(次)
0
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