Introduction:The proven radio sensitivity and the position of the thyroid gland make it a significant organ during the dental radiography exposure.Objectives:This study compared the surface radiation dose to the thyroid gland region during two different techniques of two dimensional(2D)conventional orthopantomography(OPG)and three dimensional(3D)OPG reconstructed from cone beam computed tomography(CBCT).Methods:The entrance surface dose to the thyroid region of the patients was evaluated using a personal dosimeter in a sample of 156 patients who prescribed for an OPG examination.Results:The obtained mean dose values for conventional OPG and reconstructed OPG from CBCT are 7.47μSv and 28.65μSv,respectively.Further a significant difference(p<0.05)was observed between those two doses.Conclusions:A significant amount of dose reduction to the thyroid gland region can be obtained when using conventional OPG compared to the CBCT.