Additive manufacturing in radiation oncology:a review of clinical practice, emerging trends and research opportunities

• 来源期刊: 极端制造(英文)
• 年，卷（期）: 2020,（1）
• 所属期刊栏目: TOPICAL REVIEWS
• 页码范围: 47-67
• 页数: 21页
• 语种: 中文

摘要

The additive manufacturing (AM) process plays an important role in enabling cross-disciplinary research in engineering and personalised medicine. Commercially available clinical tools currently utilised in radiotherapy are typically based on traditional manufacturing processes, often leading to non-conformal geometries, time-consuming manufacturing process and high costs. An emerging application explores the design and development of patient-specific clinical tools using AM to optimise treatment outcomes among cancer patients receiving radiation therapy. In this review, we:? highlight the key advantages of AM in radiotherapy where rapid prototyping allows for patient-specific manufacture? explore common clinical workflows involving radiotherapy tools such as bolus, compensators, anthropomorphic phantoms, immobilisers, and brachytherapy moulds;and? investigate how current AM processes are exploited by researchers to achieve patient tissue-like imaging and dose attenuations. Finally, significant AM research opportunities in this space are highlighted for their future advancements in radiotherapy for diagnostic and clinical research applications.