<strong>Introduction: </strong>Pain with neuropathic characteristics is one of the most limiting as a consequence of injury or disease that affects the somatosensory system. <strong>Objective: </strong>An assessment protocol is proposed to quantify the impact of neuropathic pain integrating personal, clinical, work and social aspects and to establish guidelines in its management and evolutionary control. <strong>Method:</strong> The medical literature on neuropathic pain and its impact is reviewed as a basis for including the variables that must be part of the protocol. <strong>Results:</strong> The variables are quantified individually and by groups of factors. The final result is stratified into four grades (mild, moderate, severe, extreme), which will serve for the subsequent control, monitoring and prevention of risks. <strong>Conclusion:</strong> The proposed protocol evaluates the impact of neuropathic pain in all aspects of the person who suffers it and quantifies the results establishing degrees for its control, follow-up and clinical, social and occupational intervention.