High Prevalence of Hepatitis B Virus Infection Compared to Human Immunodeficiency Virus among Blood Donors in Bangui

• 作者: Armelo Thibaut Yangba Kalebanga Benoît Elowa Bernard Bessanguem Eveline Mofini Georges Service Joseph Roger Molowa Kobendo Nathalie Philomène Boua-Akélélo Peggy Guéréndo Serges Magloire Camengo Police Tolmbaye Sem Fiacre Odilon
• 来源期刊: 肠胃病学期刊(英文)
• 学科: 医学
• 关键词: Hepatitis B Virus Infection HIV Blood Donors Bangui
• 年，卷（期）: 2020,（6）
• 页码范围: 137-143
• 页数: 7页
• 分类号: R51

摘要

<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:Verdana;"> Hepatitis B Virus (HBV) and Human Immunodeficiency Virus </span><span style="font-family:Verdana;">(HIV) infection is a public health problem worldwide, particularly in sub-Saharan </span><span style="font-family:""><span style="font-family:Verdana;">Africa. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> to compare the epidemiological, clinical and biological characteristic</span></span><span style="font-family:""><span style="font-family:Verdana;">s of chronic HBV and HIV infection in blood donors at the National Center for Blood Transfusion (NCBT) in Bangui. </span><b><span style="font-family:Verdana;">Patients and Methods:</span></b><span style="font-family:Verdana;"> This was an 8-month analytical cross-sectional study from August 10, 2011 to April 9, 2012. During this study, we consecutively enrolled consenting blood donors of both sexes in which the search for HBsAg and HIV infection was </span><span><span style="font-family:Verdana;">carried out. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> During the study period, 850 blood donors were collected</span></span><span style="font-family:Verdana;">. H</span><span style="font-family:Verdana;">BsAg was found in 142 donors (16.7%), of whom 55 blood donors (6.5%</span><span style="font-family:Verdana;">) were coinfected with HIV. On the other hand, HIV serology was positive in 77 blood donors (9.1%) including 55 co-infected (6.5%) with HBV. In order to better compare the risk factors, we have not included HIV-HBV coinfected patients. Only 795 blood donors were selected for the risk factor study. There were 87 cases of HBsAg positive (10.9%) and 22 cases of HIV positive (2.8%). </span><span style="font-family:Verdana;">The average age of HIV and HBV infected patients was 25.7 and 26.2 years</span><span style="font-family:Verdana;">, </span><span style="font-fam