Long term data record (1944-2018) of climatological conditions in the Lake Kinneret and its watershed ecosystems was statistically evaluated and the impact of Anthropogenic operations was included as well. Precipitation input source is obviously uncontrolled natural component whilst the other three regional water outflows pathways are under anthropogenic control: Evapo-transpiration (ET), Runoff and underground flows. Indications for climate change expressed as air warming with consequences on regional (watershed and the lake) water resources and consumption capacities policy in the drainage basin and in the Lake are discussed. The decline of air temperature from 1940 to 1970s is probably due to a change in the Albedo effect. After the decline air temperature was twisted towards elevation. Climate change caused a decline in rainfall, followed by a reduction of Jordan and other river discharges and underground flows, accompanied by a decline of WL. With respect to climate change, water allocation for agricultural consumption was shrunk.