A wide and increasing range of different technologies, devices, platforms, applications and services are being used every day by home users. In parallel, home users are also experiencing a range of different online threats and attacks. Indeed, home users are increasingly being targeted as they lack the knowledge and awareness about potential threats and how to protect themselves. The increase in technologies and platforms also increases the burden upon a user to understand how to apply and manage security across the differing technologies, operating systems and applications. Different factors such as age, education, age and gender can have an impact on information security management and awareness. This research tries to investigate and examine the effect of gender differences on information security management and online safety for internet users. An online questionnaire has been conducted and collected 434 participants (311 males and 132 females). The results show that there is a significant difference between males and females in four of the eight identified security practices and aspects. The findings show that males are likely to have better information security behaviour and being protected online more than females.