Association of Serum Chemerin Levels with Coronary Artery Disease: Pathogenesis and Clinical Research

• 作者: Ali Ozyıldız Hakan Duman Lutfu Askin Okan Tanriverdi
• 来源期刊: Cardiovascular Innovations and Applications
• 学科: 医学
• 关键词: atherosclerosis CHEMERIN heart failure coronary artery disease infl ammation metabolic syndrome
• 年，卷（期）: 2020,（2）
• 页码范围: 251-256
• 页数: 6页
• 分类号: R58

摘要

Recent studies have revealed that chemerin plays an essential role in the development of cardiovascular diseases.Autopsy studies found a strong correlation between the secretion of chemerin in peripheral tissues and aortic and coronary atherosclerosis.Plasma chemerin is a marker of systemic infl ammation and is associated with metabolic syndrome.Chemerin plays a vital role in vascular infl ammation and atherogenesis.Plasma chemerin levels are increased in patients with dilated cardiomyopathy,and chemerin is associated with left ventricular dysfunction.In this review,we focus on chemerin expression,chemerin processing,its biological function,and its role in the diagnosis of cardiovascular diseases.