Non-Alcoholic Fatty Liver Disease as a Coronary Heart Disease Severity Predictor

• 作者: Ahmed Abdel-Rady Ahmed Hussein Hossam Ismael Mohamed Shazly Mohammed Tag-Adeen
• 来源期刊: 临床医学国际期刊(英文)
• 学科: 医学
• 关键词: NAFLD FIBROSCAN Gensini SCORE
• 年，卷（期）: 2020,（4）
• 页码范围: 182-192
• 页数: 11页
• 分类号: R57

摘要

Background and Aim: Association of non-alcoholic fatty liver disease (NAFLD) and liver related mortality is well-known;however;its cardiovascular risk remains questionable. The aim of this work was to highlight the association between NAFLD and the severity of coronary heart disease. Method: The study was conducted between July and December 2019 at Qena university hospital, Qena, Egypt on patients who were scheduled for coronary angiography. Liver steatosis was diagnosed using FibroScan and the severity of coronary artery occlusion was assessed by Gensini score calculation. Statistical analysis was done to study the correlation between liver steatosis and angiography findings. Result: A total of 100 patients were included, mean age 48 years (±8 SD). Correlation between coronary angiography and the baseline variables revealed statistically significant positive correlation between Gensini score and ALT (p = 0.002), FBS (p Conclusion: NAFLD is an independent cardiovascular risk predictor with statistically significant increase in Gensini score with the higher grades of NAFLD.