Wet cupping is a simple and minor procedure practiced in Ayurveda and various traditional medicine system worldwide.In Ayurveda wet cupping therapy is practiced under the scope of Raktamo Kshana(therapeutic bloodletting)which is adopted to remove vitiated Rakta(blood).The present work is aimed to explore the wet cupping therapy from Ayurveda perspective along with global scenario.In this review,classical Ayurveda text and PubMed,Cochrane library,science direct,Google scholar and DHARA database were scrutinized for worldwide work on wet cupping therapy.The Ayurveda science can utilize these researches in completing its lost knowledge and also provide integrative effort in re-validation and enrichment of WCT which are required at large for greater benefit of the mankind.The method of WCT application,principles,indications,contraindications,complications and probable mode of action from Ayurveda perspective and global scenario were introduced and summarized.