Assessment of Anti-Salmonella Activity of Aqueous and Ethanolic Extract of Senna siamae, Used in Traditional Management of Salmonellosis in Benin

• 作者: Arnaud Soha Brice Boris Legba Césaire Ayena Christelle Lougbegnon Esther Deguenon Hornel Koudokpon Jerrold Agbankpe Kafayath Fabiyi Lamine Baba-Moussa Victorien Dougnon
• 来源期刊: 药理与制药(英文)
• 学科: 数学
• 关键词: Salmonella spp. Senna siamea SALMONELLOSIS MIC
• 年，卷（期）: 2020,（9）
• 页码范围: 226-234
• 页数: 9页
• 分类号: O17

摘要

Recent ethnopharmacological data cited <i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> as one of the most widely used medicinal plants in the management of salmonellosis in Benin. However,</span><span> </span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">data related to its activity on non-typhoidal Salmonella spp are limited. This study aimed to assess the antibacterial activity of </span><i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> on multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">. Ethanolic and aqueous extracts of </span><i><span style="font-family:Verdana;">S. siamea</span></i><span style="font-family:Verdana;"> were tested for their antibacterial activity on four multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">: </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;"> Typhimurium ATCC 14028 and three </span><i><span style="font-family:Verdana;">Salmonella </span></i><span style="font-family:Verdana;">spp</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">. </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">isolated from animals intended for human consumption in Benin. Well diffusion technique combined with the determination by microdilution of Minimum Bactericidal Concentration (MBC) and Minimum Inhibitory Concentration (MIC) were used for antibacterial testing. From antibacterial testing, inhibition diameters of the extracts</span><i> </i><span style="font-family:Verdana;">ranged from 7 to 11 mm, for the susceptible strains. Colistin (reference antibiotic) was active on all </span><i><span style="font-family:Verdana;">Salmonella spp.</span></i><span style="