Objective To study the core technology in the field of vaccines from the perspective of patents,so as to provide reference for China’s vaccine research and development(R&D)enterprises when formulating development strategies.Methods Social network analysis combined with various central indicators was used to identify the core technologies in the vaccine field and the market value of the identified core technologies was evaluated through recency-frequency-monetary(RFM)customer market value assessment model.Finally,the Condorcet voting method was applied for prediction.Results and Conclusion At present,the core technology of the vaccine field is concentrated in A61P31,which has both technical and market value with great potentials.Based on this,this paper proposes that China’s vaccine industry should shift the focus of R&D from the disease treatment to prevention.R&D enterprises should also follow the overall development trend to carry out vaccine R&D activities.