Apatinib,S-1 Combined with Paclitaxel Perfusion in the Treatment of Malignant Seroperitoneum of Gastric Cancer

• 作者: Aimin Zang Dan Hong Lin An Shenyong Su Wenwen Li Yan Shi Yaning Wei Zhiyu Wang Zhuoqi Zhang
• 来源期刊: 抗癌研究
• 学科: 医学
• 关键词: Apatinib S-1 combined with paclitaxel Malignant seroperitoneum of gastric cancer
• 年，卷（期）: kayj_2020,（4）
• 页码范围: 16-18
• 页数: 3页
• 分类号: R73

摘要

Objective:To analyze the effect of apatinib,S-1 combined with paclitaxel perfusion on malignant seroperitoneum of gastric cancer.Methods:From December 2019 to May 2020,172 patients with gastric cancer treated in our hospital were randomly divided into two groups:observation group and control group,86 cases each.The control group adopted the method of S-1 combined with paclitaxel perfusion therapy in the treatment of malignant seroperitoneum of gastric cancer.The observation group was given oral apatinib on the basis of S-1 combined with paclitaxel perfusion therapy,and the dosage was 500 mg/d.Results:The total effective treatment in the control group was 43.02%,while the total effective rate in the observation group was 69.77%;the drug resistance of the two groups of patients increased and the adverse reactions were low.Conclusion:Apatinib and S-1 combined with paclitaxel perfusion therapy can effectively improve the treatment effect,stabilize the patient's condition,increase the patient's drug resistance to adverse reactions,and have a good prognosis.