The polymer micelles and application in tumor targeted therapy system

• 作者: Bao-Wei Cui Jing-Cheng Song Shu-Di Yang Yue Gao
• 来源期刊: TMR肿瘤
• 学科: 医学
• 关键词: Polymeric micelles CARRIER ANTICANCER TARGETED
• 年，卷（期）: 2020,（6）
• 页码范围: 257-264
• 页数: 8页
• 分类号: R73

摘要

The current cancer chemotherapy drugs are inefficient and highly toxic,thus selecting the appropriate new forms of cancer treatment has become one of the important tasks.On the basis of domestic and foreign research,the composition,characteristics and main preparation methods of polymeric micelles,particularly the targeted polymeric micelles are illustrated.This review introduces different targeted polymeric micelles used as an anticancer drug carrier.By making use of the inside microenvironment of tumor cells,the preparation of a variety of new polymeric micelles with slight side effects and powerful effect in vitro and vivo,which can achieve effective control of drug release,is promising in application.