Air pollution and chronic obstructive pulmonary disease

• 作者: Duan Rui-Rui Hao Ke Yang Ting
• 来源期刊: 慢性疾病与转化医学（英文）
• 关键词: Air pollution Chronic obstructive pulmonary disease Air pollutant Health effect
• 年，卷（期）: 2020,（4）
• 所属期刊栏目: Review
• 页码范围: 260-269
• 页数: 10页
• 语种: 中文
• DOI: 10.1016/j.cdtm.2020.05.004

摘要

There is considerable epidemiological evidence indicating that air pollution has adverse effects on human health and is closely related to respiratory diseases, including chronic obstructive pulmonary disease (COPD). These effects, which can be divided into short- and long-term effects, can manifest as an exacerbation of existing symptoms, impaired lung function, and increased hospitalization and mortality rates. Long-term exposure to air with a high concentration of pollutants may also increase the incidence of COPD. The combined effects of different pollutants may become more complex in the future; hence, there is a need for more intensive research on specific at-risk populations, and formulating corresponding protective strategies is crucial. We aimed to review the epidemiological evidence on the effect of air pollution on COPD, the possible pathophysiological mechanisms underlying this effect, as well as protective measures against the effects of air pollutants in patients with COPD.