Recent advances in nonlinear optics for bio-imaging applications

• 作者: Junle Qu Liwei Liu Rui Hu Sheng Ren Silu Zhang Yihua Zhao Zhigang Yang Zilin Li
• 来源期刊: 光电进展（英文版）
• 年，卷（期）: 2020,（10）
• 所属期刊栏目: Review
• 页码范围: 13-30
• 页数: 18页
• 语种: 英文
• DOI: 10.29026/oea.2020.200003

摘要

Nonlinear optics, which is a subject for studying the interaction between intense light and materials, has great impact on various research fields. Since many structures in biological tissues exhibit strong nonlinear optical effects, nonlinear op-tics has been widely applied in biomedical studies. Especially in the aspect of bio-imaging, nonlinear optical techniques can provide rapid, label-free and chemically specific imaging of biological samples, which enable the investigation of bio-logical processes and analysis of samples beyond other microscopy techniques. In this review, we focus on the introduc-tion of nonlinear optical processes and their applications in bio-imaging as well as the recent advances in this filed. Our perspective of this field is also presented.