Acute Coronary Syndrome in a Young Male Secondary to Hyperhomocysteinemia

• 作者: Amrit Bogati Chandra Mani Adhikari Deewakar Sharma Dipanker Prajapati Kiran Prasad Acharya Mohamed Shaneez Najmy Pratima Poudel Sachin Dhungel
• 来源期刊: 心血管病(英文)
• 学科: 医学
• 关键词: HYPERHOMOCYSTEINEMIA YOUNG Myocardial Infarction Risk Factors
• 年，卷（期）: 2020,（7）
• 页码范围: 410-416
• 页数: 7页
• 分类号: R54

摘要

Homocysteine is sulfur containing intermediary amino acid formed by the demethylation of dietary methionine to cysteine. The raised serum homocysteine level is one of the important risk factors associated with coronary artery disease.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">We present a 23</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">year</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">old male with no other risk factors of coronary artery disease presented to us with acute anterior wall myocardial infarction and was treated with primary percutaneous coronary intervention. During the routine work up post percutaneous coronary intervention significant elevation of serum homocysteine level was seen with markedly low serum vitamin B12 level and was treated for it along with standard therapy for acute myocardial infarction.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">The case illustrates the need to incorporate a plasma homocysteine level during work up of coronary artery disease especially in young patients, more importantly in those without any conventional risk factors.