Genetic and Phylogenetic Characterization of a Chikungunya Virus Imported into Shenzhen, China

• 来源期刊: 中国病毒学
• 年，卷（期）: 2020,（1）
• 页码范围: 115-119
• 页数: 5页
• 语种: 英文

摘要

Dear Editor, Chikungunya virus (CHIKV) is a mosquito-borne virus belonging to the family Togaviridae,genus Alphavirus,and was first isolated in Tanzania in the 1950s (Silva and Dermody 2017;Weaver and Lecuit 2015).Human infections with CHIKV typically result in a rapid-onset febrile disease,with symptoms that include fever,headache,rash,severe joint and muscle pain,as well as prolonged periods of disability in some patients (Weaver and Lecuit 2015;Silva and Dermody 2017).Unlike other arboviral diseases such as dengue and Zika fever,the majority of CHIKV infections in humans results in clinical symptoms,with ～ 15％ of human infections who are asymptomatic with seroconversion (Schwartz and Albert 2010;Weaver and Lecuit 2015).CHIKV has been reported in more than 110 countries and territories in Asia,Africa,Europe,and the Americas (CDC 2019),and has evolved into three main lineages,including West African,Asian,and East Central South African (ECSA) (Silva and Dermody 2017;Weaver and Lecuit 2015).