Cryoablation for liver metastasis from solid pseudopapillary tumor of the pancreas: A case report

• 作者: Ji-Bing Chen Juan-Juan Shi Ke-Chen Xu Li-Zhi Niu Yang-Yang Ma
• 来源期刊: 世界临床病例杂志
• 学科: 医学
• 关键词: Solid pseudopapillary TUMOR PANCREAS Liver METASTASIS CRYOABLATION INTERVENTIONAL EMBOLIZATION Case report
• 年，卷（期）: sjlcblzz,（2）
• 页码范围: 398-403
• 页数: 6页
• 分类号: R73

摘要

BACKGROUND Solid pseudopapillary tumor(SPT) of the pancreas is a rare pancreatic tumor and 10% to 15% of cases are associated with metastasis. Cryoablation is a new method that can induce tumor necrosis, and treatment of tumors by cryoablation can cause anti-tumor immune responses.CASE SUMMARY A 16-year-old woman with SPT of the pancreas developed liver metastases 5.3 years after complete resection of the primary pancreatic tumor. She was admitted with chief complaints of abdominal pain in the upper abdomen and a weight loss of approximately 5 kg over 4 mo. Carbohydrate antigen(CA) 125,carcinoembryonic antigen, and CA 199 were normal. An abdominal computed tomography scan found multiple nodules in the right lobe of the liver that measured approximately 13.5 cm × 10.8 cm × 21.4 cm. Immunohistochemical staining results showed that CD10 and CD56 were positive, and the patient was diagnosed with SPT of the pancreas with liver metastasis. The patient underwent percutaneous cryoablation and interventional embolization. During the 5-year follow-up, the patient remained disease-free after cryoablation, with relatively normal immune function.CONCLUSION Herein, we for the first time report the treatment of liver metastasis from SPT of the pancreas using cryoablation plus interventional embolization, which could be a promising alternative therapy for pancreatic SPT liver metastasis.