Active surveillance as a management strategy for papillary thyroid microcarcinoma

• 作者: Biyun Qian Huan Zhang Juntian Liu Ming Gao Xiangqian Zheng
• 来源期刊: 癌症生物学与医学（英文版）
• 年，卷（期）: 2020,（3）
• 页码范围: 543-554
• 页数: 12页
• 语种: 英文
• DOI: 10.20892/j.issn.2095-3941.2019.0470

摘要

Active surveillance (AS) can be considered as a treatment strategy for low risk papillary thyroid microcarcinoma (PTMC), with the absence of clinically apparent lymph nodes, extrathyroidal extensions, and distant metastasis. After reviewing the reports on AS of low risk PTMCs worldwide, we introduced AS, and discussed the selection criteria for active surveillance candidates based on different guidelines and the follow-up schedules. Moreover, the requirement of cytological diagnosis, progression evaluation methods, necessity of thyrotropin suppression, and medical costs were issues that both clinicians and patients considered. The usefulness of AS for low risk PTMC patients depended on accurate and confidential evaluation of patient risk. Clinicians may adopt measures like dynamic monitoring, risk stratification, and making personal follow-up schedules to minimize these potential risks. By appropriately selecting PTMC patients, AS can be an effective alternative treatment to immediate surgery.