Metabolic syndrome and liver disease in the era of bariatric surgery: What you need to know!

• 作者: Dimitrios Giannis Georgios Tsoulfas Ioannis A Ziogas Konstantinos Zapsalis
• 来源期刊: 世界肝病学杂志:英文版(电子版)
• 学科: 医学
• 关键词: Metabolic syndrome Bariatric surgery Sleeve gastrectomy Gastric bypass Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Liver transplantation
• 年，卷（期）: 2020,（10）
• 页码范围: 709-721
• 页数: 13页
• 分类号: R73

摘要

Metabolic syndrome(MS)is defined as the constellation of obesity,insulin resistance,high serum triglycerides,low high-density lipoprotein cholesterol,and high blood pressure.It increasingly affects more and more people and progressively evolves into a serious issue with widespread healthcare,cost,and quality of life associated consequences.MS is associated with increased morbidity and mortality due to cardiovascular or chronic liver disease.Conservative treatment,which includes diet,exercise,and antidiabetic agents,is the mainstay of treatment,but depends on patient compliance to medical treatment and adherence to lifestyle modification recommendations.Bariatric surgery has recently emerged as an appropriate alternative treatment with promising longterm results.Sleeve gastrectomy and Roux-en-Y gastric bypass constitute the most commonly performed procedures and have been proven both cost-effective and safe with low complication rates.Liver transplantation is the only definitive treatment for end-stage liver disease and its utilization in patients with nonalcoholic steatohepatitis has increased more than fivefold over the past 15 years.In this review,we summarize current state of evidence on the surgical treatment of MS.