Quality of Life in Ovarian-Cancer Patients Receiving Chemotherapy

• 作者: Annekathryn Goodman Shahana Pervin Tohmina Akhter
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: Quality of Life EORTC QLQ C30 EORTC QOL OV-28 Ovarian Cancer CHEMOTHERAPY Bangladesh
• 年，卷（期）: azzlyw_2020,（11）
• 页码范围: 695-714
• 页数: 20页
• 分类号: R73

摘要

<strong>Background: </strong><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">Ovarian cancer accounts for 4% of cancers occurring in women and ranks first in gynecological cancer mortality. Maintaining and improving quality of life is an important goal of cancer treatment. The toxicities of cancer treatment particularly chemotherapy can impact an individual’s wellbeing. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> Assessment of quality of life among ovarian cancer patients receiving chemotherapy.</span><b><span style="font-family:Verdana;"> Method: </span></b><span style="font-family:Verdana;">A descriptive study was conducted among 202 patients with ovarian cancer treated at the National Institute of Cancer Research and Hospital in Bangladesh. Ethical approval was received from the ethics committee of NICRH. Data was collected using the EORTC QLQC30 questionnaire and the ovarian cancer specific EORTC QOL OV-28 module. Functional, symptomatic and global variables were scored and analyzed by SPSS. Multiple linear regressions determined the effects of predictor variables and correlation of the global health status with other variables. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">48.6% </span><span style="font-family:Verdana;">of patients were ages 41 to 50 years. The mean score of global health status was</span><span style="font-family:Verdana;"> 55.77. Deteriorating emotional function, distressing physical and psychological symptoms, sexual dysfunction and financial difficulties adversely affect the quality of life. Their correlation with global health status was strongly significant (P value < 0.05). Fatigue (r value </span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">0.604;p < 0.05) loss of appetite (r value </span><span style="font-family:Verdana;">-</span><span style="f