Apatinib as an alternative therapy for advanced hepatocellular carcinoma

• 作者: Man-Qing Cao Ti Zhang Xi-Hao Zhang Xiu-Xiu Li
• 来源期刊: 世界肝病学杂志:英文版(电子版)
• 学科: 医学
• 关键词: Apatinib Hepatocellular carcinoma ANGIOGENESIS Vascular endothelial growth factor receptor 2
• 年，卷（期）: sjgbxzzywbdzb_2020,（10）
• 页码范围: 766-774
• 页数: 9页
• 分类号: R73

摘要

Angiogenesis plays an important role in the occurrence and development of tumors.Registered tyrosine kinase inhibitors targeting vascular endothelial growth factor reduce angiogenesis.Apatinib,a tyrosine kinase inhibitor,can specifically inhibit vascular endothelial growth factor receptor 2,showing encouraging anti-tumor effects in a variety of tumors including advanced hepatocellular carcinoma(HCC).This article intends to review the clinical research and application prospects of apatinib in the field of HCC.