Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis

• 作者: Erwin TSCHACHLER Leopold ECKHART Lu-lu WANG Maria GSHWANDTNER
• 来源期刊: 当代医学科学(英文)
• 学科: 医学
• 关键词: cerebellar degeneration-related antigen 1 SKIN KERATINOCYTE mast cell
• 年，卷（期）: 2020,（3）
• 页码范围: 570-573
• 页数: 4页
• 分类号: R37

摘要

Cerebellar degeneration-related antigen 1(CDR1)was described to be expressed in the nervous system and in different types of cancer tissues.In the present study,we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis,dermis and isolated skin cells.Both CDR1 mRNA and protein were detected in human skin-derived mast cells,melanocytes,fibroblasts and keratinocytes,suggesting that CDR1 does not have a neuron-specific function.