Pleomorphic adenoma of the trachea:A case report and review of the literature

• 作者: Hua-Peng Yu Hui-Zhen Fan Li-Chang Chen Qian-Nuan Liao Shu-Bing Chen Xi He Xi-Ping Wu Ze-Kui Fang
• 来源期刊: 世界临床病例杂志
• 学科: 医学
• 关键词: Pleomorphic adenoma TRACHEA BRONCHOSCOPY REVIEW DIAGNOSIS Case report
• 年，卷（期）: 2020,（23）
• 页码范围: 6026-6035
• 页数: 10页
• 分类号: R73

摘要

BACKGROUND Pleomorphic adenoma(PA)is the most common benign tumor that occurs in the salivary glands;however,tracheobronchial PA is rarely observed.To the best of our knowledge,fewer than 50 cases have been reported in the literature.We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea.CASE SUMMARY A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years.Laboratory tests showed an elevated white blood cell count,absolute neutrophil count,and percentage of neutrophils.A chest computerized tomography scan showed a well-defined,softtissue density lesion measuring 2.4 cm×2.1 cm in the lower trachea.Flexible bronchoscopy revealed that nearly 90%of the tracheal lumen was obstructed.The histopathological and immunohistochemistry features suggested PA of the trachea.Furthermore,we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years.CONCLUSION Tracheobronchial PA occurs without gender predominance,mostly in the lower or upper trachea,and has a low recurrence rate.The median age at diagnosis is 48 years.The most common symptoms are cough,stridor,dyspnea,and wheezing.