Modification of Proliferation and Morphology in Human Umbilical Vein Endothelial Cells via in vitro High-Frequency, Low-Energy, Linear-Focused, Continuous Ultrasound Stimulation

• 作者: DU Hui Lin LAI Jiao Jiao SUN An Yu
• 来源期刊: 生物医学与环境科学（英文版）
• 年，卷（期）: 2020,（9）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 727-730
• 页数: 4页
• 语种: 英文
• DOI: 10.3967/bes2020.096

摘要

Since the bioeffects of ultrasound were discovered, its use has become widespread in the field of therapeutics[1]. Two classes of ultrasound bioeffects on tissues and cells are known: thermal and non-thermal[2]. Ultrasound exhibiting thermal bioeffects is primarily applied to cancer and tumor ablation for cell necrosis[3]. Ultrasound displaying non-thermal bioeffects is generally adapted for tendon healing, bone regeneration, and angiogenesis via cell proliferation and differentiation[4]. These bioeffects of ultrasound are closely related to ultrasound parameters. Among these influential factors, the ultrasound frequency, energy emission, and stimulation duration play important roles[5].